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| Wk | Date | Opp | Score | | 1 | September 13 | San Francisco 49ers | 16-20 L | | 2 | September 20 | @Jacksonville Jaguars | 31-17 W | | 3 | September 27 | Indianapolis Colts | 10-31 L | | 4 | Bye Week | | 5 | October 11 | Houston Texans | 28-21 W | | 6 | October 18 | @Seattle Seahawks | 27-3 W | | 7 | October 25 | @New York Giants | 24-17 W | | 8 | November 1 | Carolina Panthers | 21-34 L | | 9 | November 8 | @Chicago Bears | 41-21 W | | 10 | November 15 | Seattle Seahawks | 31-20 W | | 11 | November 22 | @St. Louis Rams | 4:05 PM | | 12 | November 29 | @Tennessee Titans | 1:00 PM | | 13 | December 6 | Minnesota Vikings | 4:15 PM | | 14 | December 14 | @San Francisco 49ers | 8:30 PM | | 15 | December 20 | @Detroit Lions | 1:00 PM | | 16 | December 27 | St. Louis Rams | 4:05 PM | | 17 | January 3 | Green Bay Packers | 4:15 PM |
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| | According to the team, Chike Okeafor (back) will not play against the Rams in Week 11. |
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| | Steve Breaston was again limited by a knee injury in Cardinals practice on Thursday, according to the team. |
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| | Adrian Wilson was limited in practice today while nursing a groin injury, according to the Cardinals' official website. |
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| More player notes. |
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